{"id":2467,"date":"2021-11-25T09:08:16","date_gmt":"2021-11-25T09:08:16","guid":{"rendered":"https:\/\/dod.nycu.edu.tw\/?page_id=2467"},"modified":"2022-08-30T13:45:22","modified_gmt":"2022-08-30T13:45:22","slug":"%e6%9e%97%e5%85%83%e6%95%8f-%e5%8d%9a%e5%a3%ab-d-d-s-m-sc-hons-ph-d-2","status":"publish","type":"page","link":"https:\/\/dod.nycu.edu.tw\/?page_id=2467","title":{"rendered":"\u6797\u5143\u654f \u535a\u58eb D.D.S., M.Sc.(Hons), Ph.D."},"content":{"rendered":"\n
\"\"<\/figure>\n\n\n

\u7d93\u6b77\uff1a<\/strong><\/p>\n

\u73fe\u5728\u8077\u4f4d<\/strong>: \u570b\u7acb\u967d\u660e\u5927\u5b78\u7259\u91ab\u5b78\u6559\u6388 (2021\/02\/01\u81f3\u4eca)\uff0c\u967d\u660e\u5927\u5b78\u6821\u53cb\u7e3d\u6703\u526f\u79d8\u66f8\u9577\uff0c\u4e2d\u83ef\u7259\u91ab\u5b78\u6703\u526f\u79d8\u66f8\u9577\u3001\u53e3\u8154\u7d44\u7e54\u5de5\u7a0b\u8207\u751f\u6280\u6750\u6599\u7814\u7a76\u6240\u6240\u9577
\u806f\u7d61\u96fb\u8a71<\/strong>\uff1a(02) 2826-7301
\u50b3\u771f\u96fb\u8a71<\/strong>\uff1a(02) 2826-4053
\u96fb\u5b50\u90f5\u4ef6<\/strong>\uff1a\u00a0ymlin@nycu.edu.tw<\/a><\/p>\n

\u8fa6\u516c\u5ba4<\/strong>: \u7259\u91ab\u7cfb\u9928 423\u5ba4
\u5be6\u9a57\u5ba4<\/strong>\uff1a\u7259\u91ab\u7cfb\u9928
Room 304 \u6750\u6599\u5408\u6210\u5be6\u9a57\u5ba4
Room 218 \u7d30\u80de\u57f9\u990a\u5be6\u9a57\u5ba4
Room 110 \u6750\u6599\u6aa2\u6e2c\u5be6\u9a57\u5ba4
Room 112 \u6578\u4f4d\u88fd\u9020\u5be6\u9a57\u5ba4<\/p>\n

\u5b78\u6b77<\/strong>\uff1a
\u82f1\u570b\u502b\u6566\u5e1d\u570b\u5b78\u9662 (Imperial College London) \u5316\u5de5\u535a\u58eb (PhD in Biomaterials and Tissue Engineering) at Department of Chemical Engineering
\u82f1\u570b\u502b\u6566\u5927\u5b78\u7687\u540e\u746a\u9e97\u5b78\u9662 (Queen Mary, University of London) \u751f\u7269\u6750\u6599\u78a9\u58eb (MSc (hons) in Biomedical Materials) at IRC in biomedical materials ?
\u570b\u7acb\u967d\u660e\u5927\u5b78 (National Yang-Ming University) \u7259\u91ab\u5b78\u58eb (DDS, Doctor of Dental surgery)<\/p>\n

\u7d93\u6b77<\/strong>\uff1a
\u967d\u660e\u5927\u5b78\u6821\u53cb\u7e3d\u6703\u526f\u79d8\u66f8\u9577
\u4e2d\u83ef\u7259\u91ab\u5b78\u6703\u526f\u79d8\u66f8\u9577
\u570b\u969b\u671f\u520a\u8ad6\u6587\u5be9\u67e5\u59d4\u54e1 (Journal of Dental Science \u548c Biomatter)
\u570b\u5bb6\u8003\u8a66\u5178\u8a66\u59d4\u54e1<\/p>\n

\u7814\u7a76\u65b9\u5411<\/h4>\n

1.3D\u5217\u5370\u5149\u805a\u5408\u6a39\u8102(light-cured resins for 3D printing)<\/strong><\/p>\n

\u672c\u9805\u7814\u7a76\u9818\u57df\u662f\u57fa\u65bc\u79d1\u6280\u90e8\u4e4b\u7a4d\u5c64\u88fd\u9020\u6574\u5408\u578b\u8a08\u756b\u6240\u884d\u751f\u51fa\u4f86\u7684\u7814\u7a76\u9818\u57df. \u5728\u9019\u4e09\u5e74\u7684\u8a08\u756b\u4e2d, \u6211\u5011\u5df2\u7814\u767c\u51fa\u4e0b\u5217\u6578\u7a2e\u6750\u6599.\u5305\u62ec\u81e8\u6642\u5047\u72593D\u5217\u5370\u6750\u6599\uff0c\u5168\u53e3\u5047\u72593D\u5217\u5370\u6750\u6599\u8207\u690d\u7259\u5c0e\u677f\u6750\u6599\u3002\u57fa\u65bc\u9019\u4e9b\u7814\u767c\u6210\u679c\uff0c\u6211\u5011\u5df2\u7d93\u6280\u8f49\u51fa\u4e00\u5bb6\u516c\u53f8\uff0c\u4e26\u4e14\u5b78\u751f\u4e5f\u6210\u7acb\u4e86\u4e00\u5bb6spin-off\u516c\u53f8\u3002<\/p>\n

2.\u7d30\u80de\u5305\u8986\u7528\u5149\u805a\u5408\u6750\u6599(light-cured materials for cell encapsulation)<\/strong><\/p>\n

\u50b3 \u7d71\u7684\u7259\u5468\u6216\u662f\u9aa8\u518d\u751f\u65b9\u6cd5, \u50cf\u662f\u5f15\u5c0e\u9aa8\u518d\u751f\u8853\u518d\u751f\u8853, \u9700\u8981\u57f7\u884c\u7ffb\u74e3\u624b\u8853, \u5c07\u4e00\u4e9b\u751f\u7269\u6d3b\u6027\u9676\u74f7\u690d\u5165\u5230\u9700\u518d\u751f\u7684\u5730\u65b9. \u4f46\u662f\u50cf\u662f\u751f\u7269\u73bb\u7483\u548c\u6c2b\u6c27\u78f7\u7070\u77f3\u7b49\u751f\u7269\u6d3b\u6027\u9676\u74f7\u6750\u6599\u56e0\u70ba\u662f\u7c89\u72c0\u7684\u95dc\u4fc2, \u81e8\u5e8a\u4e0a\u5f88\u96e3\u5c07\u4e4b\u7dca\u5bc6\u7684\u690d\u5165\u5230\u9aa8\u7f3a\u640d\u7684\u5730\u65b9. \u690d\u5165\u4e4b\u5f8c\u9019\u4e9b\u6750\u6599\u4e5f\u53ef\u80fd\u6703\u88ab\u9ad4\u6db2\u6c96\u5237\u6389, \u56e0\u6b64\u4ed6\u5011\u4e26\u975e\u7406\u60f3\u7684\u7d30\u80de\u8f09\u9ad4. \u6211\u5011\u7b2c\u4e8c\u500b\u5728\u505a\u7684\u751f\u7269\u6750\u6599, \u662f\u4ee5gelatin\u7b49\u5929\u7136\u6750\u6599\u70ba\u9aa8\u67b6\u7684\u5149\u805a\u5408\u6c34\u4ea4(light-cured hydrogel). \u9019\u500b\u6c34\u81a0\u5728\u8207\u5149\u8d77\u59cb\u5291\u4e00\u8d77\u6eb6\u65bc\u6c34\u4e4b\u5f8c, \u53ef\u4ee5\u5728\u88ab\u53ef\u898b\u5149\u6216\u662f\u7d2b\u5916\u5149\u7167\u5f8c\u5f8c\u5f9e\u6eb6\u6db2\u8f49\u8b8a\u70ba\u81a0\u9ad4. \u5982\u6b64\u4e00\u4f86\u5c31\u53ef\u4ee5\u5728\u81e8\u5e8a\u4e0a\u8f15\u6613\u7684\u5c07\u6b64\u542b\u6709\u7d30\u80de\u7684\u652f\u67b6\u6ce8\u5c04\u5230\u9aa8\u7f3a\u640d\u8655, \u4e26\u7528\u7167\u5149\u52a0\u4ee5\u56fa\u5b9a, \u4ee5\u9054\u5230\u7d44\u7e54\u518d\u751f\u7684\u6548\u679c. \u5728\u7d44\u7e54\u5de5\u7a0b\u8207\u7d30\u80de\u6cbb\u7642\u7684\u61c9\u7528\u4e0a, \u5229\u7528\u6c34\u81a0\u4f86\u5305\u8986\u7d30\u80de\u8f03\u4e00\u822c\u7684\u76f4\u63a5\u6ce8\u5c04\u7d30\u80de\u6216\u662f\u690d\u5165\u9577\u6709\u7d30\u80de\u7684\u5b54\u6d1e\u6027\u652f\u67b6\u6709\u4e0b\u5217\u512a\u52e2: \u88ab\u5305\u8986\u5728\u6c34\u81a0\u4e2d\u7684\u7d30\u80de\u662f\u4ee53D\u7684\u65b9\u5f0f\u751f\u9577, \u7136\u800c\u9577\u5728\u652f\u67b6\u4e0a\u7684\u7d30\u80de\u662f\u4ee52D\u55ae\u5c64 (monolayer) \u7684\u65b9\u5f0f\u751f\u9577. \u56e0\u6b64, \u88ab\u5305\u8986\u6642, \u7d30\u80de\u7684\u751f\u9577\u74b0\u5883\u8f03\u8fd1\u4f3c\u65bc\u5176\u518d\u5728\u9ad4\u5167\u751f\u9577\u7684\u74b0\u5883, \u4e5f\u56e0\u6b64\u662f\u4e00\u500b\u8f03\u4f73\u7684in vitro\u6a21\u578b. \u5728\u81e8\u5e8a\u7259\u79d1\u7684\u6cbb\u7642\u4e0a, \u5149\u4ea4\u9023\u6750\u6599\u5728\u5df2\u7d93\u88ab\u5927\u91cf\u61c9\u7528, \u50cf\u662f\u88dc\u7259\u7528\u7684\u6a39\u8102\u6216\u662f\u5047\u7259\u7528\u7684\u5149\u805a\u5408\u67f1\u5fc3\u9ecf\u8457\u5291. \u82e5\u8981\u7528\u65bc\u7d30\u80de\u5305\u8986, \u56e0\u70ba\u5149\u4ea4\u9023\u53cd\u61c9\u4e2d\u7684\u5149\u8d77\u59cb\u5291 (photoinitiator), \u666e\u904d\u5177\u6709\u8f03\u5f37\u7684\u6bd2\u6027, \u6240\u4ee5\u904e\u53bb\u8f03\u5c11\u5229\u7528\u5728\u6703\u8ddf\u7d30\u80de\u63a5\u89f8\u7684\u61c9\u7528\u4e0a. \u8fd1\u5e7e\u5e74\u4f86, \u5df2\u7d93\u6709\u767c\u73fe\u5e7e\u7a2e\u5149\u8d77\u59cb\u5291\u5177\u6709\u8f03\u5f31\u7684\u6bd2\u6027, \u6240\u4ee5\u53ef\u4ee5\u7528\u4f86\u61c9\u7528\u5728\u7d30\u80de\u5305\u8986\u4e2d. \u6211\u5011\u7684\u6c34\u81a0\u662f\u7531\u5408\u6210\u6750\u6599polyethylene glycol\u6216\u662f\u5929\u7136\u86cb\u767d\u8cea\u6750\u6599gelatin\u4f86\u4f5c\u70ba\u4e3b\u6210\u5206, \u7136\u5f8c\u85c9\u7531\u8207acryloyl chloride\u6216\u662fmethacrylic anhydride\u53cd\u61c9, \u5728\u5206\u5b50\u5169\u7aef\u63a5\u4e0a\u96d9\u9375, \u5206\u5225\u5408\u6210\u5206\u5b50\u91cf\u7d042000\u7684Ethylene glycol diacrylate(PEGDA2000)\u548cGelatin methacrylate (GelMa). \u9019\u5169\u7a2e\u6750\u6599\u6750\u6599\u8b8a\u5f97\u53ef\u4ee5\u66f4\u9032\u4e00\u6b65\u7684\u805a\u5408. \u8207\u7d55\u5927\u90e8\u5206UV\u5149\u805a\u5408\u6c34\u81a0\u4e0d\u540c\u7684\u5c31\u662f, \u9019\u500b\u7cfb\u7d71\u6211\u5011\u5229\u7528\u81ea\u88fd\u7684\u85cd\u5149\u5149\u6e90\u5f15\u767c\u5149\u8d77\u59cb\u5291\u7684\u4f5c\u7528, \u4f7f\u6c34\u6eb6\u6db2\u8b8a\u6210\u81a0\u9ad4. \u6211\u5011\u4e26\u5229\u7528\u5149\u8d77\u59cb\u5291VA086\u4f86\u4f5c\u70ba\u6211\u5011\u7684\u5149\u8d77\u59cb\u5291. \u5be6\u9a57\u767c\u73fe, \u6b64\u5149\u805a\u5408\u6c34\u81a0\u7cfb\u7d71\u4e26\u4e0d\u6703\u5c0d\u7d30\u80de\u9020\u6210\u5371\u5bb3, \u7d30\u80de\u53ef\u4ee5\u5305\u8986\u65bc\u5176\u4e2d\u4e26\u751f\u9577\u9054\u5230\u6578\u661f\u671f. \u5229\u7528\u9019\u7cfb\u7d71, \u6211\u5011\u53ef\u4ee5\u5728\u5169\u5206\u9418\u5167\u5c07\u6c34\u6eb6\u6db2\u786c\u5316\u70ba\u81a0\u9ad4\u4e26\u5305\u8986\u7d30\u80de. \u53e6\u5916, \u6211\u5011\u53c8\u9996\u5ea6\u5617\u8a66\u5c0d\u7d30\u80de\u65bd\u4e88n-acetylcysteine\u548cglutathione\u7b49\u6297\u6c27\u5316\u7269\u4f86\u6291\u5236\u81ea\u7531\u57fa\u5c0d\u7d30\u80de\u7522\u751f\u7684\u50b7\u5bb3. \u6211\u5011\u767c\u73fe\u6dfb\u52a0\u5c11\u91cf\u7684N-acetylcysteine\u548cglutathione\u5230\u7d30\u80de\u57f9\u990a\u6db2\u4e2d, \u53ef\u4ee5\u5927\u5e45\u964d\u4f4e\u7167\u5149\u6642\u6c34\u81a0\u805a\u5408\u6642\u7522\u751f\u7684\u7d30\u80de\u6bd2\u6027. \u5728\u53e6\u5916\u7684\u8a08\u756b\u4e2d\uff0c\u6211\u5011\u5728\u6c34\u81a0\u4e2d\u52a0\u5165\u7d93\u8868\u9762\u8655\u7406\u7684\u6c2b\u6c27\u78f7\u7070\u77f3(surface-modified hydroxyapatite), \u4f86\u6539\u8b8a\u6c34\u81a0\u7684\u6a5f\u68b0\u6027\u8cea, \u4e26\u589e\u52a0\u6c34\u81a0\u7684\u751f\u7269\u76f8\u5bb9\u6027.<\/p>\n

3.\u7259\u79d1\u518d\u751f\u6750\u6599(Regenerative dental materials)<\/strong><\/p>\n

\u00a0 \u00a0\u00a0\u672c\u7814\u7a76\u9818\u57df\u4e4b\u4e3b\u8981\u76ee\u7684\u662f\u5408\u6210\u53ef\u4ee5\u5728\u9ad4\u5167\u5206\u89e3 (biodegradable)\u7684\u751f\u7269\u6d3b\u6027\u6750\u6599\u00a0(bioactive materials), \u6216\u8005\u662f\u5c0d\u65e2\u6709\u7684\u751f\u7269\u6750\u6599\u9032\u884c\u8868\u9762\u4fee\u98fe (surface modification), \u589e\u52a0\u5176\u751f\u7269\u76f8\u5bb9\u6027 (biocompatibility). \u6211\u5011\u6709\u5408\u6210\u7259\u5468\u518d\u751f\u819c. \u7259\u5468\u518d\u751f\u819c\u662f\u5728\u505aGTR, GBR\u5f88\u91cd\u8981\u7684\u6750\u6599. \u5b83\u53ef\u4ee5\u9632\u6b62\u53e3\u8154\u4e0a\u76ae\u5411\u4e0b\u751f\u9577\u5230\u7259\u5468\u7f3a\u640d\u548c\u9aa8\u7f3a\u640d\u8655. \u65e9\u671f, \u518d\u751f\u819c\u4e3b\u8981\u662f\u5229\u7528\u9435\u6c1f\u9f8d(PTFE)\u9019\u7a2e\u4e0d\u53ef\u5206\u89e3\u7684\u6750\u6599\u4f86\u88fd\u4f5c. \u8fd1\u671f, \u8d8a\u4f86\u8d8a\u591a\u7684\u751f\u7269\u53ef\u5206\u89e3\u6750\u6599, \u50cf\u662f\u81a0\u539f\u86cb\u767d(collagen),? \u805a\u4e73\u9178(polylactide)\u548c\u805a\u4e59\u9187\u9178(polyglycolide)\u7b49\u7b49\u6750\u6599, \u90fd\u88ab\u62ff\u4f86\u88fd\u4f5c\u518d\u751f\u819c. \u6211\u5011\u5be6\u9a57\u5ba4\u662f\u5229\u7528polycaprolactone\u9019\u500b\u751f\u7269\u53ef\u5206\u89e3\u6750\u6599, \u4e26\u5229\u7528\u975c\u96fb\u7d21\u7e54\u7684\u6280\u8853, \u4f86\u88fd\u9020\u518d\u751f\u819c. \u975c\u96fb\u7d21\u7e54\u7684\u6280\u8853\u53ef\u4ee5\u88fd\u9020\u76f4\u5f91\u7d04\u6578\u767e\u5948\u7c73\u7684\u5948\u7c73\u7e96\u7dad, \u56e0\u70ba\u5176\u7e96\u7dad\u5c3a\u5bf8\u985e\u4f3c\u7d30\u80de\u5916\u57fa\u8cea\u7684\u86cb\u767d\u8cea\u5c3a\u5bf8, \u6240\u4ee5\u53ef\u4ee5\u4fc3\u9032\u7d44\u7e54\u518d\u751f\u6642\u7d30\u80de\u7684\u8cbc\u9644\u548c\u751f\u9577, \u4ee5\u53ca\u9aa8\u6bcd\u7d30\u80de\u7684\u57fa\u56e0\u8868\u73fe. \u9664\u4e86polycaprolactone\u9019\u500b\u6750\u6599\u4e4b\u5916, \u6211\u5011\u73fe\u5728\u9084\u7814\u767cpolyurethane-polycaprolactone\u5171\u805a\u5408\u7269. \u9019\u500b\u6750\u6599\u662f\u975e\u5e38\u6709\u5f48\u6027\u7684, \u4ee5\u62c9\u4f388\u500d\u65bc\u539f\u672c\u7684\u9577\u5ea6, \u9019\u6750\u6599\u53ef\u4ee5\u4f7f\u81e8\u5e8a\u64cd\u4f5c\u66f4\u70ba\u4fbf\u5229. \u53e6\u5916, \u6211\u5011\u9084\u6709\u5229\u7528\u6eb6\u6db2\u51dd\u81a0\u6cd5(sol-gel)\u4f86\u5408\u6210\u5e38\u898b\u7684\u7259\u79d1\u518d\u751f\u6750\u6599MTA (mineral trioxide aggregate).<\/p>\n

4.\u7d44\u7e54\u5de5\u7a0b (tissue engineering)\u8207\u518d\u751f\u7259\u91ab\u5b78(regenerative regenerative dentistry)<\/strong><\/p>\n

\u5229 \u7528\u7d44\u7e54\u5de5\u7a0b\u7684\u6280\u8853, \u53ef\u4ee5\u5728\u5be6\u9a57\u5ba4\u4e2d\u57f9\u990a\u51fa\u53ef\u4ee5\u81e8\u5e8a\u61c9\u7528\u7684\u4eba\u9ad4\u7d44\u7e54, \u50cf\u662f\u8edf\u9aa8 (cartilage), \u9f52\u69fd\u9aa8 (alveolar bone), \u7259\u5468\u97cc\u5e36 (periodontal ligament), \u80ba\u81df\u4e0a\u76ae(pulmonary epithelium)\u7b49\u7b49. \u5728\u7d44\u7e54\u5de5\u7a0b\u7684\u9818\u57df\u4e2d, \u5305\u62ec\u7d44\u7e54\u5de5\u7a0b\u652f\u67b6 (tissue engineering scaffold), \u7d30\u80de\u57f9\u990a\u74b0\u5883\u7684\u5efa\u7acb (define of cell culture environment), \u7d30\u80de\u548c\u751f\u7269\u6750\u6599\u7684\u4e92\u52d5 (cell-material interaction), \u7d30\u80de\u5916\u57fa\u8cea (extracellular matrix)\u548c\u7d30\u80de\u7684\u5927\u91cf\u751f\u7522\u6280\u8853 (scale up of cells)\u90fd\u662f\u975e\u5e38\u71b1\u9580\u7684\u7814\u7a76\u91cd\u9ede.\u00a0 \u518d\u751f\u7259\u91ab\u5b78, \u5c31\u662f\u5229\u7528\u5404\u7a2e\u7684\u5e79\u7d30\u80de, \u50cf\u662f\u80da\u80ce\u5e79\u7d30\u80de (embryonic stem cells), \u9593\u8449\u5e79\u7d30\u80de (mesenchymal stem cells)\u6216\u662finduced pluripotent stem cells (iPSCs)\u7b49\u7b49, \u5728\u9ad4\u5916\u57f9\u990a\u70ba\u6240\u9700\u7684\u53e3\u8154\u7d44\u7e54, \u518d\u5c07\u4e4b\u7a2e\u690d\u56de\u9ad4\u5167, \u4ee5\u9054\u6210\u5668\u5b98\u6216\u662f\u7d44\u7e54\u7684\u518d\u751f.\u00a0 \u4ee5\u7259\u79d1\u7684\u9593\u8449\u5e79\u7d30\u80de\u4f86\u8aaa, \u672c\u5be6\u9a57\u5ba4\u5177\u6709\u5206\u96e2\u8207\u57f9\u990a\u7259\u9f52\u6839\u5c16\u5e79\u7d30\u80de\u548c\u7259\u9ad3\u5e79\u7d30\u80de\u7b49\u7b49\u7684\u80fd\u529b. \u5229\u7528\u9019\u4e9b\u9593\u8449\u5e79\u7d30\u80de, \u6211\u5011\u53ef\u4ee5\u5c07\u4e4b\u5206\u5316\u70ba\u7259\u9f52\u4ee5\u53ca\u5176\u5468\u570d\u4e4b\u7d44\u7e54\u5df2\u9054\u5230\u53e3\u8154\u7d44\u7e54, \u4f8b\u5982\u9aa8\u982d\u7684\u518d\u751f. \u8981\u4f7f\u9aa8\u7f3a\u640d\u7684\u518d\u751f, \u6700\u5408\u7406\u7684\u65b9\u5f0f\u662f\u76f4\u63a5\u5c07\u8f09\u6709\u9aa8\u6bcd\u7d30\u80de (osteoblast) \u7684\u652f\u67b6\u7a2e\u690d\u5230\u9aa8\u7f3a\u640d\u8655. \u4f46\u662f\u56e0\u70ba\u9aa8\u6bcd\u7d30\u80de\u4e0d\u5bb9\u6613\u5927\u91cf\u5728\u9ad4\u5916\u57f9\u990a, \u4e26\u4e14\u5f97\u4f86\u4e0d\u6613, \u6240\u4ee5\u6211\u5011\u5e38\u5e38\u5229\u7528\u9aa8\u9ad3\u9593\u8449\u5e79\u7d30\u80de(BMSC)\u4f86\u5206\u5316\u6210 osteoblasts. \u6240\u8b02\u7684\u529f\u80fd\u6027\u7684\u751f\u7269\u53ef\u5206\u89e3\u6750\u6599\u5c31\u662f\u5728\u6750\u6599\u4e0a\u63a5\u4e0a\u53ef\u4ee5\u4f7f\u5e79\u7d30\u80de\u5206\u5316\u7684\u86cb\u767d\u8cea, \u9019\u6642\u5019\u82e5\u662f\u5e79\u7d30\u80de\u53ef\u4ee5\u57f9\u990a\u5728\u6211\u5011\u5408\u6210\u7684\u6750\u6599\u4e0a,? \u5728\u6211\u5011\u9700\u8981\u7d66\u4e88\u4e00\u822c\u7684\u57f9\u990a\u6db2, \u4e0d\u9700\u8981\u53e6\u5916\u6dfb\u52a0\u751f\u9577\u56e0\u5b50\u7b49\u7b49, \u5c31\u53ef\u4ee5\u8b93\u5e79\u7d30\u80de\u5728\u4e0a\u9762\u5206\u5316. \u8a66\u60f3\u672a\u4f86\u7684\u4e16\u754c, \u5668\u5b98\u6216\u7d44\u7e54\u53ef\u4ee5\u5f9e\u67d0\u4e9b\u5be6\u9a57\u5ba4\u8a02\u8cfc\u800c\u4f86. \u9019\u6642\u5019\u90a3\u4e9b\u5be6\u9a57\u5ba4\u53ea\u8981\u75c5\u4eba\u7684\u5e79\u7d30\u80de\u57f9\u990a\u5230\u53ef\u4ee5\u5206\u5316\u70ba\u7279\u5b9a\u7d44\u7e54\u7684\u57f9\u990a\u76bf\u4e0a, \u5c31\u53ef\u4ee5\u5c07\u8907\u96dc\u7684\u5206\u5316\u5be6\u9a57\u7c21\u5316\u5f88\u591a. \u904e\u53bb\u4e00\u5169\u5e74\u9593, \u672c\u5be6\u9a57\u5ba4\u7814\u7a76\u4e8e\u958b\u767c\u53ef\u4ee5\u4f7f\u5e79\u7d30\u80de\u5206\u5316\u5230\u9aa8\u7d30\u80de\u7684\u529f\u80fd\u6027\u6750\u6599. \u5728\u6b64\u7814\u7a76\u4e2d, \u6211\u5011\u6536\u96c6\u9aa8\u8089\u7624\u7d30\u80deMG63\u7684\u689d\u4ef6\u57f9\u990a\u6db2(conditioned medium), \u4e26\u62ff\u9019\u4e9b\u57f9\u990a\u6db2\u4f86\u57f9\u990a\u9aa8\u9ad3\u9593\u8449\u5e79\u7d30\u80de, \u4e26\u89c0\u5bdf\u662f\u5426\u6b64\u689d\u4ef6\u57f9\u990a\u6db2\u53ef\u4ee5\u5c07\u9aa8\u9ad3\u9593\u8449\u5e79\u7d30\u80de\u65b9\u5f80\u9aa8\u982d\u65b9\u5411\u5206\u5316. \u6211\u5011\u767c\u73fe, \u8ddf\u4e00\u822c\u9aa8\u5206\u5316\u7528\u7684\u9aa8\u8a98\u5c0e\u6db2(osteoinduction medium, OIM)\u76f8\u6bd4, MG63\u7684\u689d\u4ef6\u57f9\u990a\u6db2\u53ef\u4ee5\u4ee4\u9aa8\u9ad3\u9593\u8449\u5e79\u7d30\u80de\u66f4\u5feb\u66f4\u5f37\u7684\u8868\u73fe\u51faRunx2\u57fa\u56e0. \u6b64Runx2\u8f49\u8b6f\u56e0\u5b50\u7684\u8868\u73fe\u662f\u9aa8\u5206\u5316\u7684\u7684\u4e00\u500b\u5f88\u91cd\u8981\u7684\u6307\u6a19. \u78ba\u8a8dMG63\u689d\u4ef6\u57f9\u990a\u6db2\u6709\u6548\u4e4b\u5f8c, \u6211\u5011\u628aMG63\u689d\u4ef6\u57f9\u990a\u6db2\u51b7\u51cd\u4e7e\u71e5, \u5c07\u6240\u5f97\u7684\u7c89\u672b\u6eb6\u89e3\u5f62\u6210\u9ad8\u6fc3\u5ea6\u7684\u6eb6\u6db2, \u518d\u7528\u900f\u6790\u819c\u900f\u6790\u4f86\u79fb\u9664\u4e0d\u8981\u7684\u9e7d\u985e\u548c\u5176\u4ed6\u6210\u5206, \u4e4b\u5f8c\u518d\u51b7\u51cd\u4e7e\u71e5\u4e00\u6b21\u5f97\u5230\u9ad8\u7d14\u5ea6\u7684\u689d\u4ef6\u57f9\u990a\u6db2\u6fc3\u7e2e\u86cb\u767d\u8cea\u7c89\u672b. \u63a5\u4e0b\u4f86, \u6211\u5011\u5229\u7528\u4f4e\u6eab\u4e8c\u6c27\u5316\u78b3\u96fb\u6f3f\u53cd\u61c9\u5668, \u5c07polycaprolactone (PCL)\u9019\u7a2e\u7d44\u7e54\u5de5\u7a0b\u5e38\u4f7f\u7528\u7684\u751f\u7269\u53ef\u5206\u89e3\u6750\u6599\u505a\u8868\u9762\u8655\u7406, \u4f7f\u6b64\u6750\u6599\u8584\u819c\u7684\u8868\u9762\u7522\u751f\u8a31\u591a\u7684-COOH\u5b98\u80fd\u57fa. \u5229\u7528EDC\u7684\u53cd\u61c9, \u6211\u5011\u53ef\u4ee5\u5c07\u689d\u4ef6\u57f9\u990a\u6db2\u86cb\u767d\u8cea\u63a5\u4e0aPCL\u8584\u819c, \u4f7fPCL\u8b8a\u6210\u5177\u6709\u751f\u7269\u6d3b\u6027\u7684\u529f\u80fd\u6027\u6750\u6599. \u5229\u7528\u63a5\u89f8\u89d2\u6e2c\u91cf, \u6211\u5011\u767c\u73fe\u6750\u6599\u8868\u9762\u8f03\u70ba\u89aa\u6c34, \u4e26\u4e14\u5229\u7528XPS\u6e2c\u91cf\u767c\u73fe\u86cb\u767d\u8cea\u7684\u78ba\u5df2\u7d93\u9806\u5229\u63a5\u4e0aPCL\u8584\u819c\u8868\u9762. \u5229\u7528BCA assay, \u6211\u5011\u767c\u73fe\u6750\u6599\u8868\u9762\u4e0a\u63a5\u7684\u86cb\u767d\u8cea\u6703\u7de9\u6162\u7684\u91cb\u51fa. \u5728PCL\u8584\u819c\u4e0a\u57f9\u990a\u9aa8\u9ad3\u9593\u8449\u5e79\u7d30\u80de\u5f8c, \u6211\u5011\u767c\u73fe\u4e0a\u6607\u7684Runx2\u548c\u5176\u4ed6\u7684\u57fa\u56e0\u7684mRNA\u8868\u73fe, \u8b49\u5be6\u9019\u500b\u529f\u80fd\u6027\u6750\u6599\u53ef\u4ee5\u4f7f\u5e79\u7d30\u80de\u5f80\u9aa8\u982d\u65b9\u5411\u5206\u5316. \u9019\u500b\u5229\u7528\u689d\u4ef6\u57f9\u990a\u6db2\u4f86\u9054\u6210\u751f\u7269\u6750\u6599\u8868\u9762\u6d3b\u6027\u4fee\u98fe\u7684\u6982\u5ff5\u7b97\u662f\u65b0\u7a4e, \u6240\u4ee5\u53ef\u4ee5\u61c9\u7528\u5728\u4e0d\u540c\u7684\u7d30\u80de, \u9084\u6709\u7528\u5728\u672a\u4f86\u7d44\u7e54\u5de5\u7a0b\u652f\u67b6\u7684\u7814\u767c\u4e0a.<\/p>\n

5.\u6578\u4f4d\u54ac\u5408\u5668<\/strong><\/p>\n

\u5728\u6b64\u8a08\u756b\u4e2d, \u6211\u5011\u5229\u7528CCD\u4f86\u8ffd\u8e64\u4e0b\u984e\u7684\u904b\u52d5, \u6211\u5011\u5e0c\u671b\u6b64\u88dd\u7f6e\u53ef\u4ee5\u53d6\u4f86\u81e8\u5e8a\u4e0a\u5e38\u7528\u7684\u5be6\u9ad4\u54ac\u5408\u5668, \u4e26\u6e1b\u5c11\u8017\u6642\u7684\u54ac\u5408\u8abf\u6574\u6b65\u9a5f. \u6b64\u6578\u4f4d\u54ac\u5408\u5668\u4ecd\u7136\u5728\u7814\u767c\u4e2d\u3002<\/p>\n\n\n

\u7814\u7a76\u8a08\u756b\uff085\u5e74\u5167\uff09<\/strong><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\n

\u8a08\u756b\u57f7\u884c\u5e74\u9650<\/strong><\/p>\n<\/td>\n

\n

\u8a08\u756b\u540d\u7a31<\/strong><\/p>\n<\/td>\n

\n

\u8a08\u756b\u88dc\u52a9\u55ae\u4f4d<\/strong><\/p>\n<\/td>\n

\n

\u8a08\u756b\u64d4\u4efb\u5de5\u4f5c<\/strong><\/p>\n<\/td>\n<\/tr>\n

\n

2017\/09\/01~2018\/07\/31<\/p>\n<\/td>\n

\n

\u958b\u767c\u5168\u53e3\u5047\u7259\u4e4b\u6578\u4f4d\u7e3d\u9ad4\u89e3\u6c7a\u7cfb\u7d71\u8207\u6210\u7acb\u65b0\u5275\u4e8b\u696d\uff0d\u958b\u767c\u5168\u53e3\u5047\u7259\u4e4b\u6578\u4f4d\u7e3d\u9ad4\u89e3\u6c7a\u7cfb\u7d71\u8207\u6210\u7acb\u65b0\u5275\u4e8b\u696d(1\/3)(106-3114-E-010-002-)<\/p>\n<\/td>\n

\n

\u79d1\u6280\u90e8<\/p>\n<\/td>\n

\n

\u5171\u540c\u4e3b\u6301\u4eba<\/p>\n<\/td>\n<\/tr>\n

\n

2017\/08\/01~2018\/07\/31<\/p>\n<\/td>\n

\n

\u5229\u7528\u805a\u5df1\u5167\u916f\u4e19\u70ef\u9178\u8207\u5305\u542b\u7d30\u80de\u7684\u660e\u81a0\u7532\u57fa\u4e19\u70ef\u9178\u4f5c\u70ba\u751f\u7269\u5217\u5370\u6a5f\u58a8\u6c34\u5217\u5370\u51fa\u7d44\u7e54\u5de5\u7a0b\u652f\u67b6(106-2314-B-010-031-)<\/p>\n<\/td>\n

\n

\u79d1\u6280\u90e8<\/p>\n<\/td>\n

\n

\u4e3b\u6301\u4eba<\/p>\n<\/td>\n<\/tr>\n

\n

2017\/08\/01~2018\/07\/31<\/p>\n<\/td>\n

\n

\u6578\u4f4d\u5316\u7259\u79d1\u6574\u5408\u91ab\u7642\u8f14\u52a9\u7cfb\u7d71(\u91cd\u9ede\u4e3b\u984c\uff1aD4)\uff0d\u7e3d\u8a08\u756b\u517c\u5b50\u8a08\u756b\u4e09:\u6578\u4f4d\u54ac\u5408\u5668\u7684\u958b\u767c\u8207\u81e8\u5e8a\u61c9\u7528(3\/3)(106-2221-E-010-001-)<\/p>\n<\/td>\n

\n

\u79d1\u6280\u90e8<\/p>\n<\/td>\n

\n

\u5171\u540c\u4e3b\u6301\u4eba<\/p>\n<\/td>\n<\/tr>\n

\n

2017\/07\/01~2018\/06\/30<\/p>\n<\/td>\n

\n

\u50f9\u5275\u8a08\u756b\uff1a\u517c\u5177\u7f8e\u89c0\u8207\u54ac\u5408\u529f\u80fd\u4e4b\u96b1\u5f62\u6578\u4f4d\u77ef\u6b63\u5668(106-3114-8-194-002-)<\/p>\n<\/td>\n

\n

\u79d1\u6280\u90e8<\/p>\n<\/td>\n

\n

\u5171\u540c\u4e3b\u6301\u4eba<\/p>\n<\/td>\n<\/tr>\n

\n

2016\/08\/01~2017\/07\/31<\/p>\n<\/td>\n

\n

\u6578\u4f4d\u5316\u7259\u79d1\u6574\u5408\u91ab\u7642\u8f14\u52a9\u7cfb\u7d71(\u91cd\u9ede\u4e3b\u984c:D4)-\u7e3d\u8a08\u756b\u517c\u5b50\u8a08\u756b\u4e09:\u6578\u4f4d \u54ac\u5408\u5668\u7684\u958b\u767c\u8207\u81e8\u5e8a\u61c9\u7528(2\/3)\u3000<\/p>\n<\/td>\n

\n

\u79d1\u6280\u90e8<\/p>\n<\/td>\n

\n

\u5171\u540c\u4e3b\u6301\u4eba<\/p>\n<\/td>\n<\/tr>\n

\n

2015\/08\/01~2016\/07\/31<\/p>\n<\/td>\n

\n

\u6578\u4f4d\u5316\u7259\u79d1\u6574\u5408\u91ab\u7642\u8f14\u52a9\u7cfb\u7d71(\u91cd\u9ede\u4e3b\u984c\uff1aD4)\uff0d\u7e3d\u8a08\u756b\u517c\u5b50\u8a08\u756b\u4e09:\u6578\u4f4d\u54ac\u5408\u5668\u7684\u958b\u767c\u8207\u81e8\u5e8a\u61c9\u7528(1\/3)(104-2221-E-010-007-)<\/p>\n<\/td>\n

\n

\u79d1\u6280\u90e8<\/p>\n<\/td>\n

\n

\u5171\u540c\u4e3b\u6301\u4eba<\/p>\n<\/td>\n<\/tr>\n

\n

2016\/05\/01~2017\/04\/30<\/p>\n<\/td>\n

\n

\u7259\u79d1\u8d0b\u5fa9\u5143\u4ef6\u4e4b\u9ad8\u7cbe\u5ea6\u591a\u6750\u6599\u4e09\u7dad\u5217\u5370\u5c08\u5bb6\u7cfb\u7d71\u958b\u767c(3\/3)<\/p>\n<\/td>\n

\n

\u79d1\u6280\u90e8<\/p>\n<\/td>\n

\n

\u5171\u540c\u4e3b\u6301\u4eba<\/p>\n<\/td>\n<\/tr>\n

\n

2016\/04\/01~2017\/03\/31<\/p>\n<\/td>\n

\n

\u4e09\u7dad\u5217\u5370\u6a5f\u4e4b\u6a39\u8102\u6750\u6599\u6280\u8853\u670d\u52d9\u8a08\u756b<\/p>\n<\/td>\n

\n

\u53f0\u9054\u96fb\u5b50\u5de5\u696d\u516c\u53f8<\/p>\n<\/td>\n

\n

\u4e3b\u6301\u4eba<\/p>\n<\/td>\n<\/tr>\n

\n

2015\/05\/01~2016\/04\/30<\/p>\n<\/td>\n

\n

\u7259\u79d1\u8d17\u5fa9\u5143\u4ef6\u4e4b\u9ad8\u7cbe\u5ea6\u591a\u6750\u6599\u4e09\u7dad\u5217\u5370\u5c08\u5bb6\u7cfb\u7d71\u958b\u767c(2\/3)(104-2218-E-010-004-)<\/p>\n<\/td>\n

\n

\u79d1\u6280\u90e8<\/p>\n<\/td>\n

\n

\u5171\u540c\u4e3b\u6301\u4eba<\/p>\n<\/td>\n<\/tr>\n

\n

2016\/01\/01~2016\/12\/31<\/p>\n<\/td>\n

\n

\u958b\u767c\u53ef\u4ee5\u7d663D\u5217\u5370\u5168\u53e3\u5047\u7259\u4f7f\u7528\u7684\u5047\u7259\u57fa\u5e95\u6750\u6599<\/p>\n<\/td>\n

\n

\u53f0\u5317\u69ae\u6c11\u7e3d\u91ab\u9662<\/p>\n<\/td>\n

\n

\u5171\u540c\u4e3b\u6301\u4eba<\/p>\n<\/td>\n<\/tr>\n

\n

2015\/01\/01~2015\/12\/31<\/p>\n<\/td>\n

\n

\u958b\u767c\u53ef\u4ee5\u5229\u7528\u5149\u7167\u805a\u5408\u7684\u660e\u81a0-\u6c2b\u6c27\u71d0\u7070\u8907\u5408\u9f52\u69fd\u9aa8\u88dc\u9aa8\u6750\u6599<\/p>\n<\/td>\n

\n

\u53f0\u5317\u69ae\u6c11\u7e3d\u91ab\u9662<\/p>\n<\/td>\n

\n

\u5171\u540c\u4e3b\u6301\u4eba<\/p>\n<\/td>\n<\/tr>\n

\n

2014\/05\/01~2015\/04\/30<\/p>\n<\/td>\n

\n

\u7259\u79d1\u8d17\u5fa9\u5143\u4ef6\u4e4b\u9ad8\u7cbe\u5ea6\u591a\u6750\u6599\u4e09\u7dad\u5217\u5370\u5c08\u5bb6\u7cfb\u7d71\u958b\u767c(1\/3)(103-2218-E-010-004-)<\/p>\n<\/td>\n

\n

\u79d1\u6280\u90e8<\/p>\n<\/td>\n

\n

\u5171\u540c\u4e3b\u6301\u4eba<\/p>\n<\/td>\n<\/tr>\n

\n

2013\/08\/01~2014\/12\/31<\/p>\n<\/td>\n

\n

\u958b\u767c\u53ef\u4ee5\u61c9\u7528\u5728\u62d4\u7259\u50b7\u53e3\u6b62\u8840\u7684\u6c34\u805a\u5408\u751f\u7269\u81a0(102-2314-B-010-011-)<\/p>\n<\/td>\n

\n

\u79d1\u6280\u90e8<\/p>\n<\/td>\n

\n

\u4e3b\u6301\u4eba<\/p>\n<\/td>\n<\/tr>\n

\n

2011\/08\/01~2012\/12\/31<\/p>\n<\/td>\n

\n

\u5229\u7528\u751f\u7269\u5217\u5370\u6280\u8853\u88fd\u9020\u5e36\u6709\u8840\u7ba1\u7db2\u8def\u7684\u7d44\u7e54\u5de5\u7a0b\u652f\u67b6<\/p>\n<\/td>\n

\n

\u56b4\u6176\u9f61\u91ab\u5b78\u57fa\u91d1\u6703<\/p>\n<\/td>\n

\n

\u4e3b\u6301\u4eba<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n

\u73fe\u6709\u4e4b\u5be6\u9a57\u5ba4\u8a2d\u5099<\/strong><\/p>\n\n\n\n\n\n\n\n
\n

\u7269\u6750\u6599\u5408\u6210\u8207\u6539\u8cea\u8a2d\u5099<\/strong>
1. \u5948\u7c73\u7e96\u7dad\u975c\u96fb\u6210\u578b\u6a5f (nanofiber electrospinning unit)
2. Low frequency (40KHz)\u96fb\u6f3f\u53cd\u61c9\u5668 (plasma reactor)
3. \u5674\u9727\u4e7e\u71e5\u6a5f (spray dryer)
4. 4\u4f4d\u6578\u7cbe\u5ea6\u96fb\u5b50\u5929\u5e73 (scale)
5. \u8ff4\u8f49\u5f0f\u771f\u7a7a\u6fc3\u7e2e\u6a5f (rotary evaporator)
6. \u63a5\u89f8\u89d2\u6e2c\u91cf\u5100 (contact angle meter)
7. \u8ca080\u5ea6C\u51b7\u51cd\u51dd\u7d50\u69fd (cold trap)
8. \u8ca040\u5ea6C\u4f4e\u6eab\u5faa\u74b0\u6c34\u69fd (low temperature circulator)
9. \u6cb9\u8ff4\u8f49\u771f\u7a7a\u5e6b\u6d66 (vacuum pump)
10. \u65cb\u8f49\u5857\u4f48\u6a5f (spin coater)
11. \u9ad8\u626d\u529b\u76f4\u6d41\u652a\u62cc\u6a5f(DC stirrer )
12. \u7d2b\u5916\u5149\u9375\u7d50\u7bb1 (UV crosslinker)
13. 12\u516c\u5347\u52a0\u71b1\u578b\u8d85\u97f3\u6ce2\u6d17\u6de8\u6a5f (untrasonic cleaner)
14. 72\u516c\u5347\u5f37\u5236\u9001\u98a8\u5faa\u74b0\u70e4\u7bb1 (oven)
15. \u9178\u9e7c\u5ea6\u6e2c\u5b9a\u5100 (pH meter)
16. \u771f\u7a7a\u70e4\u7bb1 (vacuum oven)
17. \u96fb\u5b50\u63a7\u6eab\u52a0\u71b1\u652a\u62cc\u5668 (magnetic stirrer)
18. \u5316\u5b78\u62bd\u6c23\u6ac3 (chemical hood)
19. 1700\u5ea6\u8d85\u9ad8\u6eab\u70e4\u7bb1
20. \u96fb\u52d5\u7be9\u5b50
21. \u5404\u5f0f\u947d\u5e8a\u8207\u5207\u5272\u6a5f<\/p>\n<\/td>\n

\n

\u7d30\u80de\u57f9\u990a\u8a2d\u5099<\/strong>
1. \u751f\u7269\u64cd\u4f5c\u6ac3 (laminar flow hood)
2. \u9ad8\u6eab\u6ec5\u83cc\u4e8c\u6c27\u5316\u78b3\u57f9\u990a\u7bb1 (decontamination CO2 incubator)
3. \u96e2\u5fc3\u6a5f (centrifuge)
4. \u76f4\u7acb\u5f0f\u986f\u5fae\u93e1 (upright microscope)
5. \u51b7\u51cd\u96e2\u5fc3\u6a5f (refrigerated centrifuge)
6. \u5fae\u91cf\u5206\u6ce8\u5668 (micropipette)
7. 4\u5ea6C\u51b7\u85cf\u6ac3 (fridge)
8. -20\u5ea6C\u51b0\u6ac3 (freezer)
9. \u7121\u96fb\u5b50\u63a7\u6eab\u52a0\u71b1\u652a\u62cc\u5668 (magnetic stirrer)
10. \u9694\u819c\u5e6b\u6d66 (diaphragm pump)
11. \u6db2\u614b\u6c2e\u7b52 (liquid nitrogen tank)<\/p>\n<\/td>\n<\/tr>\n

\n

\u6578\u4f4d\u751f\u7522\u88fd\u9020\u8a2d\u5099<\/strong>
1. \u4e09\u7dad\u684c\u4e0a\u578bCNC\u5207\u5272\u6a5f (CNC machine)
2. 5\u8ef8\u7259\u79d1\u7528CNC\u5207\u5272\u6a5f
3. \u81ea\u88fd3\u7dad\u5217\u5370\u6a5f3\u53f0 (DLP)
4. Form1 3D printer (SLA)
5. FDM 3D printer
6. \u9ede\u81a0\u6a5f
7. \u53e3\u8154\u6383\u7784\u6a5f<\/p>\n<\/td>\n<\/tr>\n

\n

\u6750\u6599\u6aa2\u6e2c\u5100\u5668<\/strong>
1. \u9ecf\u5ea6\u8a08(\u6d41\u8b8a\u5100)
2. \u5085\u7acb\u8449\u8f49\u63db\u7d05\u5916\u7dda\u5149\u8b5c\u5100
3. \u986f\u5fae\u62c9\u66fc\u5149\u8b5c\u5100
4. \u8868\u9762\u786c\u5ea6\u8a08
5. \u5149\u8b5c\u5100
6. \u6bd4\u8272\u6a5f
7. \u8868\u9762\u4eae\u5ea6\u8a08
8. \u5bc6\u5ea6\u8a08
9. \u78e8\u8017\u6e2c\u8a66\u6a5f
10. \u63a5\u89f8\u89d2\u6e2c\u8a66\u5100<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n

\u767c\u8868\u8457\u4f5c(*:\u901a\u8a0a\u4f5c\u8005)<\/strong><\/p>\n\n\n\n

\u671f\u520a\u8ad6\u6587:<\/strong><\/p>\n\n\n

    \n
  1. Su JJ-M, Lin C-H, Chen H, Lee S-Y, Lin Y-M. Biofabrication of Cell-Laden Gelatin Methacryloyl Hydrogels with Incorporation of Silanized Hydroxyapatite by Visible Light Projection. Polymers<\/em>. 2021; 13(14):2354.<\/li>\n
  2. Hsuan Chen, Dong-Hui Cheng, Shou-Chieh Huang, Yuan-Min Lin, Comparison of flexural properties and cytotoxicity of interim materials printed from mono-LCD and DLP 3D printers, The Journal of Prosthetic Dentistry, 2020, ISSN 0022-3913,<\/li>\n
  3. Chen, H.; Lee, S.-Y.; Lin, Y.-M. Synthesis and Formulation of PCL-Based Urethane Acrylates for DLP 3D Printers. Polymers<\/em>2020, 12<\/em>, 1500.<\/li>\n
  4. Lin, Y.-M., Chen, H.<\/a>, Lin, C.-H.<\/a>, Huang, P.-J.<\/a>and Lee, S.-Y.<\/a> (2020), “Development of polycaprolactone\/hydroxyapatite composite resin for 405 nm digital light projection 3D printing”, Rapid Prototyping Journal<\/a>, Vol. 26 No. 5, pp. 951-958.<\/li>\n
  5. Chih-Hsin Lin, Yuan-Min Lin (co-first author), Yu-Lin Lai and Shyh-Yuan Lee, Mechanical properties, accuracy, and cytotoxicity of UV-polymerized 3D printing resins composed of BisEMA, UDMA, and\/or TEGDMA, Journal of Prosthetic Dentistry, 2020, vol 123(2)<\/li>\n
  6. Chih\u2010Hsin Lin, Jimmy Jiun\u2010Ming Su, Shyh\u2010Yuan Lee, Yuan\u2010Min Lin*<\/sup>, Stiffness Modification of Photopolymerizable Gelatin\u2010Methacrylate Hydrogels Influences Endothelial Differentiation of Human Mesenchymal Stem Cells. Journal of Tissue Engineering and Regenerative Medicine, 2018 Oct;12(10):2099-2111<\/li>\n
  7. Shyh-Yuan Lee, Sheng-Chien Wu, Hsuan Chen, and Yuan-Min Lin*<\/sup>, \u201cSynthesis and Characterization of Polycaprolactone-Based Polyurethanes for the Fabrication of Elastic Guided Bone Regeneration Membrane,\u201d BioMed Research International, vol. 2018, Article ID 3240571, 13 pages, 2018.<\/li>\n
  8. Jy-Jiunn Tzeng, Yi-Ting Hsiao, Yun-Ching Wu, Hsuan Chen, Shyh-Yuan Lee, and Yuan-Min Lin*<\/sup>, \u201cSynthesis, Characterization, and Visible Light Curing Capacity of Polycaprolactone Acrylate,\u201d BioMed Research International, vol. 2018, Article ID 8719624, 8 pages, 2018.<\/li>\n
  9. Chang, Wei-Ting; Hsu, Huang Jan; Jiang, Cho-Pei; Lee, Shyh-Yuan; Lin, Yuan-Min\uff0a<\/sup>“Effects of titanium dioxide and tartrazine lake on Z-axis resolution and physical properties of resins printed by visible-light 3D printers”, Rapid Prototyping Journal, 2018, Vol. 24 Issue: 1, pp.160-165<\/li>\n
  10. Chih-Hsin Lin, Ming-Chau Chang, Shih-Chieh Hung, Shyh-Yuan Lee, Yuan-Min Lin*<\/sup>, Bioactive surface modification of polycaprolactone using MG63-conditioned medium can induce osteogenic differentiation of mesenchymal stem cells , Journal of Materials Science, 2017. 52(7):p3967-3978<\/li>\n
  11. Yung\u2010Chang Cheng*, Deng\u2010Huei Lin, Cho\u2010Pei Jiang, Yuan\u2010Min Lin*<\/sup>, Dental implant customization using numerical optimization design and 3\u2010dimensional printing fabrication of zirconia ceramic, International Journal for Numerical Methods in Biomedical Engineering, doi:1002\/cnm.2820.<\/li>\n
  12. Chih-Hsin Lin, Kai-Fung Lin, Kwei Mar, Shyh-Yuan Lee, Yuan-Min Lin*<\/sup>, Antioxidant N-acetylcysteine and glutathione increase the viability and proliferation of MG63 cells encapsulated in the gelatin-methacrylate\/VA-086\/blue light hydrogel system, Tissue Engineering, 2016, 22(8):p792-800<\/li>\n
  13. Chih-Hsin Lin, Shyh-Yuan Lee, Yuan-Min Lin*<\/sup>, Plasma treatment in conjunction with EGM-2 medium increases endothelial and osteogenic marker expressions of bone marrow mesenchymal stem cells, Journal of Materials Science, 2016. 51(19):p.9145-9154<\/li>\n<\/ol>\n\n\n

    \u5df2\u7372\u5f97\u8207\u7533\u8acb\u4e2d\u4e4b\u5c08\u5229<\/strong><\/p>\n\n\n\n

    \u5e8f\u865f<\/td>\u5df2<\/strong>\u7372\u5f97\u5c08\u5229\u8cc7\u6599<\/td>\u767c\u660e\u4eba<\/td>\u5c08\u5229\u6240\u6709\u6b0a\u4eba<\/td><\/td><\/tr>
    1<\/td>\u53ef\u5149\u805a\u5408\u7684\u751f\u7269\u53ef\u5206\u89e3\u805a\u5408\u7269\u53ca\u5176\u88fd\u5099\u65b9\u6cd5(\u5c08\u5229\u5df2\u6838\u51c6\uff0c\u5c08\u5229\u865f105109680)<\/td>\u6797\u5143\u654f, \u9ec3\u54c1\u5112, \u6c5f\u5353\u57f9, \u674e\u58eb\u5143<\/td>\u570b\u7acb\u967d\u660e\u5927\u5b78<\/td><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n
    \u5e8f\u865f
    <\/td>    		\u7533\u8acb\u4e2d\u5c08\u5229\u8cc7\u6599<\/td>\u767c\u660e\u4eba<\/td> \u5c08\u5229\u6240\u6709\u6b0a\u4eba <\/td><\/tr>
    1<\/td>\u7528\u65bc\u4e09\u7dad\u5217\u5370\u4e4b\u751f\u7269\u53ef\u5206\u89e3\u7684\u5149\u805a\u5408\u7d44\u5408\u7269 (\u53f0\u7063\u7533\u8acb\u865f105109677)<\/td>\u6797\u5143\u654f, \u6797\u8ce2\u9054, \u6c5f\u5353\u57f9, \u674e\u58eb\u5143
    <\/td>    		\u570b\u7acb\u967d\u660e\u5927\u5b78<\/td><\/tr>
    2<\/td>\u7259\u79d1\u7528\u54ac\u5408\u904b\u52d5\u8ffd\u8e64\u88dd\u7f6e(\u7f8e\u570b\u7533\u8acb\u6848\u865f15\/387,072,\u53f0\u7063\u7533\u8acb\u865f106105087)<\/td>\u6797\u5143\u654f, \u674e\u58eb\u5143, \u912d\u91cf\u5143, \u8a31\u81f3\u745c<\/td>\u570b\u7acb\u967d\u660e\u5927\u5b78<\/td><\/tr>
    3<\/td>\u4e09\u7dad\u5217\u5370\u7528\u7259\u79d1\u6750\u6599\u53ca\u5176\u88fd\u5099\u65b9\u6cd5\u8207\u61c9\u7528(\u7533\u8acb\u865f106118743)<\/td>\u6797\u5143\u654f, \u9673\u7ffe, \u9ec3\u54c1\u5112, \u674e\u58eb\u5143<\/td>\u570b\u7acb\u967d\u660e\u5927\u5b78<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"

    \u7d93\u6b77\uff1a \u73fe\u5728\u8077\u4f4d: \u570b\u7acb\u967d\u660e\u5927\u5b78\u7259\u91ab\u5b78\u6559\u6388 (2021\/02\/01\u81f3\u4eca)\uff0c\u967d\u660e\u5927\u5b78\u6821\u53cb\u7e3d\u6703\u526f\u79d8\u66f8\u9577\uff0c\u4e2d\u83ef\u7259\u91ab\u5b78 […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-2467","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/dod.nycu.edu.tw\/index.php?rest_route=\/wp\/v2\/pages\/2467","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dod.nycu.edu.tw\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/dod.nycu.edu.tw\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/dod.nycu.edu.tw\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dod.nycu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2467"}],"version-history":[{"count":4,"href":"https:\/\/dod.nycu.edu.tw\/index.php?rest_route=\/wp\/v2\/pages\/2467\/revisions"}],"predecessor-version":[{"id":2848,"href":"https:\/\/dod.nycu.edu.tw\/index.php?rest_route=\/wp\/v2\/pages\/2467\/revisions\/2848"}],"wp:attachment":[{"href":"https:\/\/dod.nycu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2467"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}