{"id":1984,"date":"2021-06-29T17:11:29","date_gmt":"2021-06-29T17:11:29","guid":{"rendered":"https:\/\/dod.nycu.edu.tw\/?page_id=1984"},"modified":"2026-02-21T13:43:18","modified_gmt":"2026-02-21T13:43:18","slug":"%e6%a5%8a%e6%94%bf%e6%9d%b0-%e5%89%af%e6%95%99%e6%8e%88yang-cheng-chieh","status":"publish","type":"page","link":"https:\/\/dod.nycu.edu.tw\/?page_id=1984","title":{"rendered":"\u694a\u653f\u6770 \u6559\u6388(Yang, Cheng-Chieh)"},"content":{"rendered":"\n
\"\"<\/figure>\n\n\n<\/p>\n

\u7d93\u6b77\uff1a<\/strong><\/p>\n\n\n

\u7562\u696d\u5b78\u6821<\/strong><\/td>\u570b\u5225<\/strong><\/td>\u4e3b\u4fee\u7cfb\u5225<\/strong><\/td>\u5b78\u4f4d<\/strong><\/td>\u5e74\u5ea6<\/strong><\/td><\/tr>
\u5fb7\u5dde\u5927\u5b78\uff0cMD Anderson\u764c\u75c7\u4e2d\u5fc3<\/td>\u7f8e\u570b<\/td>\u5206\u5b50\u53ca\u7d30\u80de\u816b\u7624\u5b78\u7cfb<\/td>\u535a\u58eb<\/td>2004 ~ 2009<\/td><\/tr>
\u570b\u7acb\u967d\u660e\u5927\u5b78(\u73fe\u6539\u540d \u570b\u7acb\u967d\u660e\u4ea4\u901a\u5927\u5b78 ) <\/td>\u4e2d\u83ef\u6c11\u570b<\/td>\u7259\u91ab\u5b78\u7cfb<\/td>\u7259\u91ab\u5b78\u58eb<\/td>1988 ~ 1994<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n

\u7d93\u6b77\uff1a<\/strong><\/h4>\n\n\n
\u670d\u52d9\u55ae\u4f4d<\/strong><\/td>\u670d\u52d9\u90e8\u9580<\/strong><\/td>\u8077\u7a31<\/strong><\/td>\u670d\u52d9\u671f\u9593<\/strong><\/td><\/tr>
\u570b\u7acb\u967d\u660e\u4ea4\u901a\u5927\u5b78<\/td>\u7259\u91ab\u5b78\u7cfb<\/td>\u7cfb\u4e3b\u4efb<\/td>2019 ~2025<\/td><\/tr>
\u4e2d\u83ef\u6c11\u570b\u53e3\u8154\u984e\u9762\u5916\u79d1\u5b78\u6703<\/td>\u570b\u969b\u4e8b\u52d9\u59d4\u54e1\u6703 \u8cc7\u8a0a\u59d4\u54e1\u6703<\/td>\u59d4\u54e1<\/td>2012 ~\u81f3\u4eca<\/td><\/tr>
\u4e2d\u83ef\u6c11\u570b\u53e3\u8154\u984e\u9762\u5916\u79d1\u5b78\u6703<\/td><\/td>\u5c08\u79d1\u91ab\u5e2b<\/td>2002 ~<\/td><\/tr>
\u570b\u7acb\u967d\u660e\u4ea4\u901a\u5927\u5b78<\/td>\u7259\u91ab\u5b78\u7cfb<\/td>\u526f\u6559\u6388<\/td>2011 ~<\/td><\/tr>
\u53f0\u5317\u69ae\u6c11\u7e3d\u91ab\u9662<\/td>\u53e3\u8154\u91ab\u5b78\u90e8<\/td>\u4e3b\u6cbb\u91ab\u5e2b<\/td>2010 ~\u81f3\u4eca<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n

\u73fe\u8077\uff1a<\/strong><\/h4>\n

\u570b\u7acb\u967d\u660e\u4ea4\u901a\u5927\u5b78 \u7259\u91ab\u5b78\u7cfb \u6559\u6388<\/p>\n

\u53f0\u5317\u69ae\u6c11\u7e3d\u91ab\u9662\uff0c\u53e3\u8154\u984e\u9762\u5916\u79d1 \u4e3b\u6cbb\u91ab\u5e2b<\/p>\n

\u5c08\u9577\uff1a<\/strong>\u53e3\u8154\u984e\u9762\u5916\u79d1\u624b\u8853\u3001\u764c\u75c7\u751f\u7269\u5b78\u3001\u7d30\u80de\u8a0a\u865f\u50b3\u5c0e\u8def\u5f91\u3001T\u00a0<\/span>\u7d30\u80de\u514d\u75ab\u7642\u6cd5\u65bc\u53e3\u8154\u764c\u6cbb\u7642\u3001\u764c\u75c7\u7684DNA<\/span>\u7532\u57fa\u5316\u7570\u5e38<\/p>\n\n\n

\u806f\u7d61\u96fb\u8a71<\/strong>\uff1a(02) 2826-7100<\/p>\n\n\n\n

\u50b3\u771f\u96fb\u8a71<\/strong>\uff1a(02) 2826-4053<\/p>\n\n\n\n

\u96fb\u5b50\u90f5\u4ef6<\/strong>\uff1a ccyang1124@nycu.edu.tw<\/a> ; ccyang13@vghtpe.gov.tw<\/a>\u3000<\/p>\n\n\n

\u7814\u7a76\u65b9\u5411<\/h4>\n
    \n
  1. \u53e3\u8154\u764c\u7684\u81f4\u75c5\u6a5f\u8f49\u3002<\/li>\n
  2. \u53e3\u8154\u764c\u8f49\u8b6f\u91ab\u5b78\u3002<\/li>\n
  3. \u53e3\u8154\u764c\u7684\u5316\u5b78\u9810\u9632\u3002<\/li>\n<\/ol>\n

    \u7814\u7a76\u8a08\u756b<\/h4>\n\n\n
    \u5e74 \u5ea6<\/td>\u8a08 \u756b \u540d \u7a31<\/td>\u985e   \u578b<\/td>\u57f7 \u884c \u671f \u9593<\/td>\u55ae\u4f4d<\/td><\/tr>
    2018<\/td>\u7b2c3\u671f\u764c\u75c7\u7814\u7a76\u764c\u75c7\u4e2d\u5fc3\u8a08\u756b – \u7814\u767c\u85c9\u7531\u514b\u670d\u6cbb\u7642\u6297\u6027\u548c\u5f37\u5316\u514d\u75ab\u6cbb\u7642\u4f86\u5c0d\u6297\u665a\u671f\u53e3\u8154\u764c\u7684\u65b0\u7b56\u7565<\/td>\u4e3b\u6301\u4eba<\/td>2018\/01\/01~2020\/12\/31<\/td>\u885b\u798f\u90e8<\/td><\/tr>
    2017<\/td>\u7cbe\u9032\u81e8\u5e8a\u8a66\u9a57\u80fd\u91cf\u53ca\u570b\u969b\u8e8d\u5347\u8a08\u756b<\/td>\u4e3b\u6301\u4eba<\/td>2017\/01\/01~2019\/12\/31<\/td>\u885b\u798f\u90e8<\/td><\/tr>
    2015<\/td>\u7537\u6027\u8cc0\u723e\u8499\u53d7\u5668\u5728\u53e3\u8154\u9c57\u72c0\u4e0a\u76ae\u7d30\u80de\u764c\u764c\u5316\u904e\u7a0b\u4e2d\u6240\u626e\u6f14\u89d2\u8272\u4e4b\u7814\u7a76<\/td>\u4e3b\u6301\u4eba<\/td>2015\/08\/01~2016\/07\/31<\/td>\u79d1\u6280\u90e8<\/td><\/tr>
    2014<\/td>\u5408\u4f75\u6291\u5236\u4e0a\u76ae\u751f\u9577\u56e0\u5b50\u53d7\u5668\u53ca\u7dad\u751f\u7d20A\u9178\u65bc\u8a98\u5c0e\u53e3\u8154\u764c\u7d30\u80de\u9032\u884c\u518d\u5206\u5316\u4e4b\u7814\u7a76<\/td>\u4e3b\u6301\u4eba<\/td>2014\/08\/01~2016\/07\/31<\/td>\u570b\u79d1\u6703<\/td><\/tr>
    2014<\/td>\u7b2c3\u671f\u764c\u75c7\u7814\u7a76\u764c\u75c7\u4e2d\u5fc3\u8a08\u756b – \u4ee5\u65e9\u671f\u8a3a\u65b7\u53ca\u6297\u8f49\u79fb\u6cbb\u7642\u7b56\u7565\u964d\u4f4e\u53e3\u8154\u764c\u6b7b\u4ea1\u7387<\/td>\u4e3b\u6301\u4eba<\/td>2014\/05\/01~2017\/12\/31<\/td>\u885b\u798f\u90e8<\/td><\/tr>
    2014<\/td>PRAME \u7684\u8868\u73fe\u53ca\u8abf\u63a7\u5728\u53e3\u8154\u764c\u7d30\u80de\u7684\u5206\u5316\u4e4b\u7814\u7a76<\/td>\u4e3b\u6301\u4eba<\/td>2014\/08\/01~2015\/07\/31<\/td>\u79d1\u6280\u90e8<\/td><\/tr>
    2014<\/td>\u4e0a\u76ae\u751f\u9577\u56e0\u5b50\u53d7\u5668\u7684\u523a\u6fc0\u5c0d\u7dad\u751f\u7d20A\u9178\u4e59\u578b\u53d7\u5668\u53d7PRAME\u6291\u5236\u4e4b\u5f71\u97ff\u53ca\u5c0d\u53e3\u8154\u764c\u5206\u5316\u72c0\u614b\u4e4b\u7814\u7a76<\/td>\u4e3b\u6301\u4eba<\/td>2014\/01\/01~2014\/12\/31<\/td>\u53f0\u5317\u69ae\u6c11\u7e3d\u91ab\u9662<\/td><\/tr>
    2013<\/td>\u5408\u4f75\u6291\u5236\u4e0a\u76ae\u751f\u9577\u56e0\u5b50\u53d7\u5668\u53ca\u7dad\u751f\u7d20A\u9178\u65bc\u8a98\u5c0e\u53e3\u8154\u764c\u7d30\u80de\u9032\u884c\u518d\u5206\u5316\u4e4b\u7814\u7a76<\/td>\u4e3b\u6301\u4eba<\/td>2013\/08\/01~2014\/07\/31<\/td>\u570b\u79d1\u6703<\/td><\/tr>
    2013<\/td>\u63a2\u8a0e\u8abf\u63a7\u7259\u9f52\u56ca\u6ce1\u5167\u5e79\u7d30\u80de\u4ea4\u4e92\u4f5c\u7528\u8207\u5206\u5316\u7684\u5206\u5b50\u6a5f\u5236<\/td>\u4e3b\u6301\u4eba<\/td>2013\/01\/01~2013\/12\/31<\/td>\u53f0\u5317\u69ae\u6c11\u7e3d\u91ab\u9662<\/td><\/tr>
    2012<\/td>\u4e0a\u76ae\u751f\u9577\u56e0\u5b50\u53d7\u5668\u4e4b\u8a0a\u865f\u50b3\u5c0e\u8def\u5f91\u5c0dEZH2\u7684\u8abf\u63a7\u5728\u53e3\u8154\u764c\u5316\u7684\u53bb\u5206\u5316\u904e\u7a0b\u4e2d\u6240\u626e\u6f14\u7684\u89d2\u8272\u4e4b\u7814\u7a76<\/td>\u4e3b\u6301\u4eba<\/td>2012\/08\/01~2013\/07\/31<\/td>\u570b\u79d1\u6703<\/td><\/tr>
    2012<\/td>EGFR \u8a0a\u865f\u50b3\u905e\u8def\u5f91\u5c0dPRC2\u7684\u8abf\u63a7\u5728\u53e3\u8154\u764c\u6240\u626e\u6f14\u7684\u89d2\u8272<\/td>\u4e3b\u6301\u4eba<\/td>2012\/01\/01~2012\/12\/31<\/td>\u53f0\u5317\u69ae\u6c11\u7e3d\u91ab\u9662<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n

    \u7372\u734e\u9805\u76ee<\/h4>\n\n\n
    \u5e74 \u5ea6<\/td>\u55ae  \u4f4d<\/td>\u5f97  \u734e  \u9805  \u76ee<\/td><\/tr>
    107<\/td>\u53f0\u5317\u69ae\u6c11\u7e3d\u91ab\u9662<\/td>\u6700\u4f73\u6559\u5b78\u4e3b\u6cbb\u91ab\u5e2b<\/td><\/tr>
    105<\/td>\u53f0\u5317\u69ae\u6c11\u7e3d\u91ab\u9662<\/td>\u6700\u4f73\u6559\u5b78\u4e3b\u6cbb\u91ab\u5e2b<\/td><\/tr>
    101<\/td>\u570b\u7acb\u967d\u660e\u5927\u5b78<\/td>\u6559\u5b78\u512a\u826f\u734e<\/td><\/tr>
    90<\/td>\u53f0\u5317\u69ae\u6c11\u7e3d\u91ab\u9662<\/td>\u6700\u4f73\u81e8\u5e8a\u6559\u5b78\u91ab\u5e2b<\/td><\/tr>
    89<\/td>\u53f0\u5317\u69ae\u6c11\u7e3d\u91ab\u9662<\/td>\u6700\u4f73\u81e8\u5e8a\u6559\u5b78\u91ab\u5e2b<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n

    \u671f\u520a\u8ad6\u6587<\/strong><\/h4>\n
      \n
    1. Lim E, Kuo CC, Tu HF, Yang CC<\/strong>. The prognosis outcome of Oral Squamous Cell Carcinoma using HIF-2\u03b1. Journal of the Chinese Medical Association 2017; S1726-4901(17):30161-2. (SCI). (Impact factor: 1.252;Rank: 52.58%)\u7b2c\u4e00\u6216\u901a\u8a0a\u4f5c\u8005<\/li>\n
    2. Yu EH, Tu HF, Wu CH, Yang CC<\/strong>, Chang KW.. MicroRNA-21 promotes perineural invasion and impacts survival in patients with oral carcinoma. Journal of the Chinese Medical Association 2017; 80(6):383-8. (SCI). (Impact factor: 1.252;Rank: 52.58%)\u7b2c\u56db\u6216\u4ee5\u5f8c\u4f5c\u8005<\/li>\n
    3. Lim E, Wu CH, Moi SH, Lui MT, Yang CH, Yang CC<\/strong>*. The expression of Transglutaminase 2 (TG-2) in Oral Squamous Cell Carcinoma and its Clinical Significance. Journal of the Chinese Medical Association 2017; 80(8):515-20. (SCI). (Impact factor: 1.252;Rank: 52.58%)\u7b2c\u4e00\u6216\u901a\u8a0a\u4f5c\u8005<\/li>\n
    4. Yeh CF, Li WY, Chu PY, Kao SY, Chen YW, Lee TL, Hsu YB, Yang CC<\/strong>, Tai SK.. Pretreatment pain predicts perineural invasion in oral squamous cell carcinoma: A prospective study. Oral Oncology 2016; 61:115-9 (SCI). (Impact factor: 4.794;Rank: 0.56%)\u7b2c\u56db\u6216\u4ee5\u5f8c\u4f5c\u8005<\/li>\n
    5. Yang CC<\/strong>, Tu HF, Wu CH, Chang HC, Chiang WF, Shih NC, Lee YS, Kao SY, Chang KW.. Upregulation of HB-EGF by the COX-2\/PGE2 signaling associates with the cisplatin resistance and tumor recurrence . Oral Oncology 2016; 56:54-61. (SCI). (Impact factor: 4.794;Rank: 0.56%)\u55ae\u4e00\u4f5c\u8005<\/li>\n
    6. Chen YF, Yang CC<\/strong>, Kao SY, Liu CJ, Lin SC, Chang KW.. MicroRNA-211 Enhances the Oncogenicity of Carcinogen-Induced Oral Carcinoma by Repressing TCF12 and Increasing Antioxidant Activity. Cancer Research 2016; 76(16):4872-86. (SCI). (Impact factor: 9.122;Rank: 6.68%)\u7b2c\u4e8c\u4f5c\u8005<\/li>\n
    7. Ko HW, Lee HH, Huo L, Xia W, Yang CC<\/strong>, Hsu JL, Li LY, Lai CC, Chan LC, Cheng CC, Labaff AM, Liao HW, Lim SO, Li CW, Wei Y, Nie L, Yamaguchi H, Hung MC.. GSK3\u03b2 inactivation promotes the oncogenic functions of EZH2 and enhances methylation of H3K27 in human breast cancers. Oncotarget 2016; 7(35):57131-44. (SCI). (Impact factor: 5.168;Rank: 20.05%)\u7b2c\u56db\u6216\u4ee5\u5f8c\u4f5c\u8005<\/li>\n
    8. Lu WC, Liu CJ, Tu HF, Chung YT, Yang CC<\/strong>, Kao SY, Chang KW, Lin SC.. miR-31 targets ARID1A and enhances the oncogenicity and stemness of head and neck squamous cell carcinoma . Oncotarget 2016; 7(35):57254-67. (SCI). (Impact factor: 5.168;Rank: 20.05%)\u7b2c\u56db\u6216\u4ee5\u5f8c\u4f5c\u8005<\/li>\n
    9. Tseng SH, Yang CC<\/strong>, Yu EH, Chang C, Lee YS, Liu CJ, Chang KW, Lin SC.. K14-EGFP-miR-31 transgenic mice have high susceptibility to chemical-induced squamous cell tumorigenesis that is associating with Ku80 repression. Int J Cancer. 2015; 136(6):1263-75. (SCI). \u7b2c\u4e8c\u4f5c\u8005<\/li>\n
    10. Yang CC<\/strong>, LaBaff A, Wei Y, Nie L, Xia W, Huo L, Yamaguchi H, Hsu YH, Hsu JL, Liu D, Lang J, Du Y, Lien HC, Li LY, Deng R, Chan LC, Yao J, Kleer CG, Hortobagyi GN, Hung MC.. Phosphorylation of EZH2 at T416 by CDK2 contributes to the malignancy of triple negative breast cancers. American Journal of Translational Research 2015; 7(6):1009-20. (SCI). (Impact factor: 2.829;Rank: 37.11%)\u55ae\u4e00\u4f5c\u8005<\/li>\n
    11. Lu WC, Kao SY, Yang CC<\/strong>, Tu HF, Wu CH, Chang KW, Lin SC.. EGF up-regulates miR-31 through the C\/EBP\u03b2 signal cascade in oral carcinoma. PLoS One 2014; 9(9):e108049. (SCI). (Impact factor: 2.806;Rank: 22.66%)\u7b2c\u4e09\u4f5c\u8005<\/li>\n
    12. Chang CW, Chen YS, Chou SH, Han CL, Chen YJ, Yang CC<\/strong>, Huang CY, Lo JF.. Distinct subpopulations of head and neck cancer cells with different levels of intracellular reactive oxygen species exhibit diverse stemness, proliferation, and chemosensitivity. Cancer Research 2014; 74(21):6291-305. (SCI). (Impact factor: 9.122;Rank: 6.68%)\u7b2c\u56db\u6216\u4ee5\u5f8c\u4f5c\u8005<\/li>\n
    13. Du Y, Shen J, Hsu JL, Han Z, Hsu MC, Yang CC<\/strong>, Kuo HP, Wang YN, Yamaguchi H, Miller SA, Hung MC. Syntaxin 6-mediated Golgi translocation plays an important role in nuclear functions of EGFR through microtubule-dependent trafficking. Oncogene 2014; 33(6):756-70. (SCI). (Impact factor: 7.519;Rank: 6.89%)\u7b2c\u56db\u6216\u4ee5\u5f8c\u4f5c\u8005<\/li>\n
    14. Hung PS, Tu HF, Kao SY, Yang CC<\/strong>, Liu CJ, Huang TY, Chang KW, Lin SC.. miR-31 is upregulated in oral premalignant epithelium and contributes to the immortalization of normal oral keratinocytes. Carcinogenesis 2014; 35(5):1162-71. (SCI). (Impact factor: 5.105;Rank: 20.97%) \u7b2c\u56db\u6216\u4ee5\u5f8c\u4f5c\u8005<\/li>\n<\/ol>\n\n\n

      <\/p>\n","protected":false},"excerpt":{"rendered":"

      \u7d93\u6b77\uff1a \u7562\u696d\u5b78\u6821 \u570b\u5225 \u4e3b\u4fee\u7cfb\u5225 \u5b78\u4f4d \u5e74\u5ea6 \u5fb7\u5dde\u5927\u5b78\uff0cMD Anderson\u764c\u75c7\u4e2d\u5fc3 \u7f8e\u570b \u5206\u5b50\u53ca\u7d30\u80de\u816b\u7624\u5b78 […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1984","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/dod.nycu.edu.tw\/index.php?rest_route=\/wp\/v2\/pages\/1984","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dod.nycu.edu.tw\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/dod.nycu.edu.tw\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/dod.nycu.edu.tw\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dod.nycu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1984"}],"version-history":[{"count":17,"href":"https:\/\/dod.nycu.edu.tw\/index.php?rest_route=\/wp\/v2\/pages\/1984\/revisions"}],"predecessor-version":[{"id":4625,"href":"https:\/\/dod.nycu.edu.tw\/index.php?rest_route=\/wp\/v2\/pages\/1984\/revisions\/4625"}],"wp:attachment":[{"href":"https:\/\/dod.nycu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1984"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}